Clindamycin for Dogs

Acting on Gram-positive- and Gram-negative bacteria (the two vital bacterial groups), Clindamycin is a broad-spectrum antibiotic for treating bacterial infections. Clindamycin is an antibacterial medication that effectively fights a broad spectrum of microbes that infect dogs and cats. For instance, this antimicrobial drug can deal with conditions resulting from injuries and wounds, tooth and ear infections, skin infections, bone infections, and much more.

More often, vets prescribe Clindamycin for controlling bacterial pneumonia in pets and respiratory tract infections, toxoplasmosis, and pyoderma. Sometimes this vet medication is used to treat urinary tract infections, especially in cases where the microbe is receptive to the drug. Clindamycin is most effective on bacteria capable of surviving and thriving in the absence of oxygen-anaerobic bacteria.   

Clindamycin at a Glance

Brand Name

Clintab®, ClinDrops®, Cleocin®, Antirobe®

Generic Name

Clindamycin Hydrochloride

Drug Type

Lincosamide antibiotic

Does FDA approve the Medication?


Suitable for

Cats and dogs


Only through prescription

Available Forms

Tablets (25mg and 150mg), oral suspension


Is Clindamycin Safe for Dogs?

Vets prescribe Clindamycin for managing bacterial infections in dogs (and cats as well) as the drug has the FDA’s approval. However, there are certain precautions you must keep in mind before you start administering the medication to your pet. You should avoid offering the Medication to your dog if she’s pregnant or lactating, as Clindamycin gets infused in the placenta and milk.

Moreover, you should not administer the Medication if your pet is hypersensitive to it or suffers from liver- or kidney disease. 

Clindamycin Pharmacokinetics in Pets

Depending upon the concentration levels of the active ingredient in the infected area-Clindamycin Hydrochloride-this drug’s action could be bactericidal or bacteriostatic. This antimicrobial drug is permeable and smoothly infiltrates the heart, peritoneal fluid, pleura, abscesses, joints, and bones. Clindamycin can go across the blood-brain barrier and is present in high concentrations in the CNS, particularly in the case of coexisting meningeal inflammation.

Numerous studies and trials have demonstrated the bioavailability of the drug, implying that it has a positive effect following ingestion. Clindamycin is metabolized in part in the dog’s liver and is excreted out of the body via bile, feces, and urine.

What is the Right Dosage of Clindamycin for Dogs?

As with any prescription medication, you should offer Clindamycin to your pet only if the vet prescribes the drug. The usual dosage is about 5mg/lb (11mg/kg) to be given two times a day, maintaining 12 hours. On the other hand, you can offer a single dose of 10mg/lb (22mg/kg) in 24 hours.

You can buy Clindamycin in capsule, tablet or liquid form for administering 0rally. You can offer the Medication to your pet on an empty stomach or with food but ensure that the dog drinks enough water while taking the Medication. The course or duration of treatment depends on the severity of the condition and how the pet responds to therapy.

Side Effects

The following side-effects have been reported in dogs taking Clindamycin:-

  • Constipation
  • Breathing difficulty
  • Loss of appetite
  • Hives (urticaria)
  • Bloody diarrhea
  • Vomiting
  • Allergic reaction
  • Trouble swallowing
  • Bloody stool

If you observe any of the above symptoms in your pet, you should immediately get in touch with your vet.

Drug Contraindications

Let your vet know about your dog’s medical background and any medication the pet is taking because of an existing condition. Clindamycin has been known to interact with medicines such as Loperamide, Chloramphenicol, Erythromycin, and opiates. Therefore you should not offer the antibacterial or any of the above drugs your pet might be taking.

Drug Overdose Signs and Symptoms

The usual overdosing signs and symptoms include seizures, abrupt or sudden changes in behaviour, and inexplicable weight loss. If you notice any of these signs, take your pet to the vet at the earliest or call the ASPCA Animal Poison Control Center Helpline (1-888-426-4435).


Disclaimer: The above content is based on multiple research articles referred to online. Global Dog Breeds intends to share information, but it's strictly advised to consult a veterinarian and seek advice before using any medications described. We believe each condition and dog is unique, and only after careful evaluation from a qualified professional should you be offering any medications to your pet.


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